Covid-19 Sentry

Contents

From Preprints

  1. tested by RT-PCR for SARS-CoV2 detection, and variants screening; these tests were carried out between landing and custom clearance, ii)sequenced by MiSeq Illumina. Antigenic tests and sequencing by NovaSeq were carried out on respiratory samples collected from the 56 passengers of the second flight. Results: SARS-CoV-2 RNA suspected of being from the Omicron BA.1 variant was detected on the aircraft wastewater. SARS-CoV2 RNA was detected for 11 (20%) passengers and the Omicron BA.1 variant was identified. Conclusion: Our work shows the efficiency of aircraft wastewater testing to detect SARS-CoV-2 cases among travelers and identify the viral genotype. It also highlights the low performance for incoming flights from outside Europe to France of the current filter strategy that combines requirement for a vaccine pass and a negative testing before boarding.

    🖺 Full Text HTML: SARS-CoV-2 testing of aircraft wastewater shows that mandatory tests and vaccination pass before boarding did not prevent massive importation of Omicron variant in Europe
🖺 Full Text HTML: How time-scale differences in asymptomatic and symptomatic transmission shape SARS-CoV-2 outbreak dynamics
  1. and 5% (282 (251 to 317) but was not cost-effective, using Kenya9s cost-effectiveness threshold ($ 919.11). Rapid roll-out with 30% coverage averted 63% more deaths and was more cost-saving (ICER=$-1,607 (-1,609 to -1,604) per DALY averted) compared to slow roll-out at the same coverage level, but 50% and 70% coverage scenarios were not cost- effective. Interpretation: With prior exposure partially protecting much of the Kenyan population, vaccination of young adults may no longer be cost-effective.

    🖺 Full Text HTML: Epidemiological impact and cost- effectiveness analysis of COVID-19 vaccination in Kenya

From Clinical Trials

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